The Classroom Genome Project

A WebQuest for 10th Grade (Biology)

Student Page.
Click HERE For Teacher Page.


Introduction

Have you ever wondered how two brown eyed parents can produced a blue eyed child? Or what causes mutations to occur? This Webquest is designed to aid you in discovering the answers to these questions and more. Discover how genetic material influences physical characteristics and how mutations may influence a person’s daily life.


The Task

Students are to research a specific genetic disorder and present a PowerPoint presentation on their findings.  In order to this students must first acquire basic knowledge on genotypes, phenotypes, and mutations via the Webquest. The ultimate goal of the research project is for students to have a better understanding of genetic disorders and to develop empathy for people with genetic disorders.


The Process

o  Before you reach the lab, your teacher will have assigned you to groups of 2-4 students.

o  Step 1

o   Go to: http://learn.genetics.utah.edu/content/begin/tour/

o   View the sections What is DNA, What is a gene, What is a chromosome and What is heredity (skip What is a protein and What is a trait)

o   Answer questions 1-8 on worksheet that correspond with these sections.

o  Step 2

o   Go to: http://www.teachersdomain.org/asset/hew06_int_mendelinherit/

o   Watch and read each section aloud before hitting the next button.

o   Answer questions 9-11 on the worksheet.

o   Complete Punnett square problem (question 12).

o   If you cannot complete all the questions, go to the following website for more information.

§  http://www.teachersdomain.org/asset/hew06_int_dominantgene/

§  Read aloud the section before hitting the next button.

o  Step 3

o   Go to: http://www.biostudio.com/d_%20Meiotic%20Recombination%20Between%20Linked%20Genes.htm

o   Click step through.

o   Read aloud the text.

o   Then hit play and watch the animation.

o   Hit the continue button and repeat the last two steps for each slide.

o   As you watch the animations, complete questions 13-15 on the worksheet.

o  Step 4

o   Go to: http://highered.mcgraw-hill.com/sites/0072556781/student_view0/chapter11/animation_quiz_4.html

o   Watch the video.

o   Complete the quiz at the bottom.

§  Review any incorrect answers.

o   Go to: http://www.bbc.co.uk/bitesize/higher/biology/genetics_adaptation/mutations/revision/1/

o   Skip to Gene Mutations section (pink box)

o   Look at different types of mutation.

o   Answer questions 16-19.

o  Step 5

o   Go to: http://learn.genetics.utah.edu/content/begin/traits/predictdisorder/

o   If you remember and understand what meiosis is, skip to the section on How can cells end up with too many or two few chromosomes.

§  If you don’t remember, review the first two image files.

o   Click play on the image file abnormal meiosis. Read each step aloud as you click forward.

o   Repeat this for each of the remaining 4 image files, trisomy, monosomy, deletions and translocations.

o   Answer questions 20-25 on the worksheet.

o  Step 6

o   Go to: http://learn.genetics.utah.edu/content/disorders/whataregd/

o   Check with your teacher on which level 1 or 2 disorder your group is assigned.

§  If your group gets to select a disorder, select a level 1 or 2 disorder to research.

o   Click on your disorder name.

o   Utilize the information on this page about your disorder, as well as the links on the right of the page to become experts on your disorder.

o   As a group, you will need to present information on your disorder in a 5-8 minute presentation.

o   The presentation should include (but is not limited to):

§  What is the disorder?

§  What does the disorder genotype look like (what type of mutation is it)?

§  What does the disorder phenotype look like (physical characteristics/symptoms)?

§  What is the treatment (if any) for this disorder?

§  How might this disorder effect the daily life a person with the disorder?

·         This question requires some research, but can also include examples you create yourselves.

§  Any other relevant or interesting facts.

Evaluation

The presentation will be a group grade. Students will have the opportunity to evaluate their group’s efforts individually as well.

Presentation rubric:

Multimedia Project : The Classroom Genome Project

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Teacher Name:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Student Name:     ________________________________________

 

 

 

 

 

 

 

 

CATEGORY

4

3

2

1

Presentation

Well-rehearsed with smooth delivery that holds audience attention.

Rehearsed with fairly smooth delivery that holds audience attention most of the time.

Delivery not smooth, but able to maintain interest of the audience most of the time.

Delivery not smooth and audience attention often lost.

Content

Covers topic in-depth with details and examples. Subject knowledge is excellent.

Includes essential knowledge about the topic. Subject knowledge appears to be good.

Includes essential information about the topic but there are 1-2 factual errors.

Content is minimal OR there are several factual errors.

Organization

Content is well organized using headings or bulleted lists to group related material.

Uses headings or bulleted lists to organize, but the overall organization of topics appears flawed.

Content is logically organized for the most part.

There was no clear or logical organizational structure, just lots of facts.

Sources

Source information collected for all graphics, facts and quotes. All documented in desired format.

Source information collected for all graphics, facts and quotes. Most documented in desired format.

Source information collected for graphics, facts and quotes, but not documented in desired format.

Very little or no source information was collected.

Group Evaluation:

Peer Evaluation Form

Evaluate yourself and your teammates in the following areas.

PERSONNEL EVALUATION: Please enter the names of your team members in the first row and complete the following personnel evaluation.

1 = Excellent, 2 = Good, 3 = Acceptable, 4 = Marginal, 5 = Unacceptable

 

Name of team member                                                                                

 

 

 

 

Was  prepared for class research and to begin work on project                                                                                         

 

 

 

 

During meetings offered opinions and ideas

 

 

 

 

During meetings listened to others                                                                

 

 

 

 

Accepted responsibilities and gave the project a high priority

 

 

 

 

Completed assigned tasks as promised and on time                                                                                                        

 

 

 

 

Helped to identify and clarify problems                                                                         

 

 

 

 

Was willing to discuss disagreement and adapt                                                               

 

 

 

 

Produced quality work                                                                                

 

 

 

 

Saw what had to be done and did it without prompting or pressure

 

 

 

 

 

Create a pie chart to graphically depict your assessment of the time and effort each member of your team devoted to project 2.

Conclusion

You should now understand how an individual’s genotype can influence their phenotype. How different types of mutations may occur and that mutations can cause genetic disorders. As an expert on your specific genetic disorder you should understand the genotype, physical traits or symptoms, treatments, and the impact of the disorder on a person’s daily life.

Credits & References

·       Thank you to the University of Utah for a wonderful and interactive genetics website for students!

o   http://learn.genetics.utah.edu/

·       Thank you to Teacher’s Domain for maintaining a free database of teaching media for classroom use!

o   http://www.teachersdomain.org/

·       Thank you BioStudio Visual Communications for informative animations!

o   http://www.biostudio.com/

·       Thank you McGraw Hill for informative videos and self assessments !

o   http://catalogs.mhhe.com/mhhe/home.do

·       Thank you BBC for having all kinds of cool information (and TV shows) available to people and students around the world!

o   http://www.bbc.co.uk/bitesize/higher/